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Some studies also show PEITC-mediated suppression of anti-apoptotic proteins like XIAP and survivin, which are up-regulated in cancer cells [144]

Piel normal

Height:4mm

In unstressed cells, Nrf2 is constitutively synthesized but degraded by the Nrf2-specific ubiquitin ligase complex, in which the stress-sensor molecule Keap1 directly captures Nrf2 (Figure 2)